MSC in Bioengineering
MSc in Bioengineering
- Establishment of Bioengineering Master Program was approved by the decision of the higher education executive board dated 14.12.2016.
- First students were accepted for 2017-2018 Fall Semester. Student applications for 2017-2018 Spring Semester was accepted.
- Bioengineering Graduate Plan is designed in parallel with research activities which are mostly focusing on Molecular and Cellular Bioengineering, Biomedical Technologies and Bioprocess Engineering fields.
Bioengineering Master’s Education Plan
| Core Courses | ||
| BE 500 | M.Sc. Thesis | (0-1)NC ECTS 26 |
| BE 598 | Research Seminar* | (0-2)NC ECTS 9 |
| BE 501 | Principles of Bioengineering I | (3-0)3 ECTS 9 |
| BE 502 | Principles of Bioengineering II | (3-0)3 ECTS 9 |
| BE 503 | Research and Ethics in Bioengineering | (3-0)3 ECTS 9 |
| BE 8xx | Special Studies | (8-0)NC ECTS 4 |
| Elective Courses | ||
| BE 511 | Statistics for Bioengineers | (3-0)3 ECTS 8 |
| BE 512 | Biomolecular Engineering | (3-0)3 ECTS 8 |
| BE 513 | Bioprocess Engineering | (3-0)3 ECTS 8 |
| BE 514 | Fundamentals of Medical Engineering | (3-0)3 ECTS 8 |
| BE 515 | Nanoscale Bioengineering | (3-0)3 ECTS 8 |
| BE 516 | Biomedical Device Technologies | (3-0)3 ECTS 8 |
| BE 531 | Introduction to Biomaterials Science | (3-0)3 ECTS 8 |
| BE 532 | Protein Engineering Principles | (3-0)3 ECTS 8 |
| BE 533 | Biopolymers | (3-0)3 ECTS 8 |
| BE 534 | Macromolecular Science and Engineering | (3-0)3 ECTS 8 |
| BE 535 | Drug Delivery Systems | (3-0)3 ECTS 8 |
| BE 536 | Bioprinting | (3-0)3 ECTS 8 |
| BE 537 | Personalized Medicine | (3-0)3 ECTS 8 |
| BE 538 | Neuroengineering | (3-0)3 ECTS 8 |
| BE 539 | Synthetic Biology | (3-0)3 ECTS 8 |
| BE 540 | Bioimaging Techniques | (3-0)3 ECTS 8 |
| BE 541 | Biophotonics | (3-0)3 ECTS 8 |
| BE 542 | Cellular Mechanobiology | (3-0)3 ECTS 8 |
| BE 543 | Biomicroscopy | (3-0)3 ECTS 8 |
| BE 544 | BioMEMS: Fabrication Technologies and Applications | (3-0)3 ECTS 8 |
| BE 545 | Microfluidics | (3-0)3 ECTS 8 |
| BE 546 | Stem Cell Biology and Technology | (3-0)3 ECTS 8 |
| BE 547 | Tissue Engineering and Regenerative Medicine | (3-0)3 ECTS 8 |
| BE 548 | 3D Cell Culture | (3-0)3 ECTS 8 |
| BE 549 | Nanomedicine | (3-0)3 ECTS 8 |
| BE 591 | Special Topics in Bioengineering | (3-0)3 ECTS 8 |
*All M.S. students must register Seminar course until the beginning of their 4th semester.
Total credit (min.): 21
Number of courses with credit (min): 7.
Total ECTS credit (min):120
Course Descriptions
| Core Courses | ||
| BE 500 | M.Sc. Thesis | (0-1)NC ECTS 26 |
| Under supervision of an advisor, students write a master thesis about the experimental and/or theoretical research topic they choose based on the courses they have taken. | ||
| BE 598 | Research Seminar* | (0-2)NC ECTS 9 |
| The course is composed of literature search, data collection, data analysis and reporting on the master thesis topic chosen by students under the guidance of their advisors. | ||
| BE 501 | Principles of Bioengineering I | (3-0)3 ECTS 9 |
| Course content aims to integrate principle concepts of engineering that is commonly used in bioengineering practice. Content include engineering mathematics; statics; solid mechanics; kinematics and kinetics; fluid dynamics; basic thermodynamics; circuit elements and electronic design; heat and mass transfer. | ||
| BE 502 | Principles of Bioengineering II | (3-0)3 ECTS 9 |
| This course starts with the discussion of structure and chemistry of biological molecules, enzyme kinetics, DNA replication and repair, gene expression. Followed by the recombinant DNA technology, subcellular organization, cell motility, signaling and cell division. Specific examples in applications in medicine, bionanotechnology and tissue engineering are also addressed. | ||
| BE 503 | Research and Ethics in Bioengineering | (3-0)3 ECTS 9 |
| This course starts with the discussion of research methods and techniques that are commonly used in bioengineering. The students are expected to write and present a research proposal utilizing the techniques they learned. Following research techniques the class will focusing on ethical concepts in bioengineering, using specific case studies. | ||
| BE 8xx | Special Studies | (8-0)NC ECTS 4 |
| Graduate students study on special topics regarding his/her thesis under the guidance of his/her thesis advisor. | ||
| Elective Courses | ||
| BE 511 | Statistics for Bioengineers | (3-0)3 ECTS 8 |
| This course is designed to equip bioengineering students with essential statistical tools to be used for the interpretation of data from biomedical research. Content include variation; probability; distributions; hypothesis testing; ANOVA; distribution free tests; correlation; regression; survival analysis | ||
| BE 512 | Biomolecular Engineering | (3-0)3 ECTS 8 |
| This course starts with the discussion of structure and function of biomolecules that play role in decoding the genom and transformation of energy. This is followed by enzymatic catalysis, active transport, metabolism of macromolecules and molecular recognition. In addition, design and production of novel proteins, genomes and cells, and biomolecular treatment methods will be addressed. | ||
| BE 513 | Bioprocess Engineering | (3-0)3 ECTS 8 |
| The course is designed to cover applications of engineering principles on bioprocesses where raw materials are biologically converted into valuable chemicals. It emphasizes enzyme kinetics and technology, bioreaction kinetics, design and control of bioreactors and fermenters, downstream processes of bioreaction products. | ||
| BE 514 | Fundamentals of Medical Engineering | (3-0)3 ECTS 8 |
| Cells, tissues, fundamentals of organs and systems physiology, homeostasis, human anatomy, basic information about cardiovascular, respiratory, digestive, renal, endocrine, immune, nervous, muscular and sensory systems, biomedical devices, bioelectric, artificial organs, biomaterials, biomechanics, bioimaging systems will be covered. Practical issues related to the design of medical devices will also be discussed in the course. | ||
| BE 515 | Nanoscale Bioengineering | (3-0)3 ECTS 8 |
| During the course properties of nanomaterials, characterization of nanomaterials, applications of nanomaterials for bioengineering approaches, and production of nanoscale tools for modern biotechnological research will be discussed. | ||
| BE 516 | Biomedical Device Technologies | (3-0)3 ECTS 8 |
| This course will introduce the students to the foundations of biomedical devices. The properties of a variety of sensor materials will be studied, and the structures of sensors for a variety of biomedical signals will be examined. The applications of the sensors used in the clinical practice will be covered. | ||
| BE 531 | Introduction to Biomaterials Science | (3-0)3 ECTS 8 |
| The course introduces classes of biomaterials citing their use in life sciences and technologies. This introductory course discusses material bulk and surface properties, material characterization techniques, biological responses to biomaterials, and issues regarding the production of biomaterials. | ||
| BE 532 | Protein Engineering Principles | (3-0)3 ECTS 8 |
| This course starts with the discussion of structure and biochemistry of proteins, genetic, biochemical and chemical techniques used in protein production and characterization. Followed by amino acids the building blocks of proteins, motifs found in protein structure, rational and combinatorial methods used in protein engineering. These topics will be explained with specific examples and applications. | ||
| BE 533 | Biopolymers | (3-0)3 ECTS 8 |
| During the course structure and properties of biopolymers, biological and technological importance of biopolymers, production of biopolymers and their industrial importance will be discussed. | ||
| BE 534 | Macromolecular Science and Engineering | (3-0)3 ECTS 8 |
| The course covers the following topics: introduction to macromolecular systems commonly used in bioengineering applications, physical and chemical properties of macromolecules, characterizations, polymerization mechanisms, fundamentals on macromolecular architectures, examples of macromolecular systems used in biotechnology. | ||
| BE 535 | Drug Delivery Systems | (3-0)3 ECTS 8 |
| This course has been designed to introduce fundemantals, strategies and materials used in controlled drug delivery systems to bioengineering students. The course covers pharmacokinetics/pharmacodynamics fundemantals, drug diffusion and permeation, controlled drug release concept, strategies and kinetics, macro-, micro- and nano-carriers, and specific examples of drug delivery systems. | ||
| BE 536 | Bioprinting | (3-0)3 ECTS 8 |
| Following topics will be covered in this course; properties of bioprinting materials, natural and artificial bioink materials, bioprinting techniques, applications of bioprinting. | ||
| BE 537 | Personalized Medicine | (3-0)3 ECTS 8 |
| Topics covered in this course will include current and future applications of genomics in medicine, pharmacogenomics, next generation sequencing technologies, genome-based healthcare technologies, therapeutic response, personalized implants. | ||
| BE 538 | Neuroengineering | (3-0)3 ECTS 8 |
| Existing neurotechnologies for analyzing brain signals and for treating neurological and psychiatric diseases; biophysical, biochemical, anatomical principles governing the design of current neurotechnologies, with a goal of encouraging innovations of a new generation of therapies will be covered during the course. | ||
| BE 539 | Synthetic Biology | (3-0)3 ECTS 8 |
| This course offers an introduction to synthetic biology, which is a new discipline that seeks to enable the predictable engineering of biological systems. This course will discuss the principles that are used by all organisms to perform cellular functions, and how the knowledge gained from studying naturally-occurring biological systems can be used to create artificial gene networks capable of performing new functions. Course content include DNA assembly, protein purification, cell culture, genetic and metabolic engineering, biological circuits, and the broader applications of synthetic biology. | ||
| BE 540 | Bioimaging Techniques | (3-0)3 ECTS 8 |
| This introductory course covers the physical and engineering principles for bio-imaging technologies used in medicine. It reviews the mathematical principles used in signal processing required for such systems, detectors used, and overall systems including the hardware. It covers a broad spectrum of imaging systems starting with x-ray projection imaging, moving on to x-ray CT, SPECT, PET, MRI and ultrasound. | ||
| BE 541 | Biophotonics | (3-0)3 ECTS 8 |
| During the course introduction of biophotonics, fundamental principles of light, optics, lasers, diagnostic biophotonics, therapeutic applications of biophotonics will be discussed. | ||
| BE 542 | Cellular Mechanobiology | (3-0)3 ECTS 8 |
| This course will focus on the mechanical regulation of molecular events in cellular biology. Course content include general concepts of mechanobiology; cellular framework; cytoskeletal mechanics; membrane mechanics; cellular adhesion and migration; mechanical regulation of cell fate. | ||
| BE 543 | Biomicroscopy | (3-0)3 ECTS 8 |
| Introduction to geometrical and wave optics for investigating the biological sample of interest, functioning of optical microscopes and their advantages and limitations will be covered during the course. | ||
| BE 544 | BioMEMS: Fabrication Technologies and Applications | (3-0)3 ECTS 8 |
| BioMEMS is the application of MEMS (Microelectromechanical Systems) technology in the fields of biomedical and health sciences. Due to their small size (1μm-1mm), BioMEMS have the advantages of low weight, low cost, quick response, high throughput, high efficiency, requiring much less sample/reagent, and easy system integration. BioMEMS found broad applications in disease diagnosis, prevention and treatment. Various BioMEMS products have been developed, such as microfluidic devices, neural interface devices, μTAS (micro total analysis systems), lab-on-a-chip, DNA chips, micro drug delivery system, microsurgical tools, biosensors. This course introduces to students about the fundamentals of BioMEMS technology, typical BioMEMS devices and their applications. | ||
| BE 545 | Microfluidics | (3-0)3 ECTS 8 |
| As the diversity of lab-on-a-chip systems is continuously growing, there is also an increasing demand of a better understanding of the microfluidic phenomena behind the final application. In this concept, this course will provide a theoretical background of microfluidics effects and concepts. | ||
| BE 546 | Stem Cell Biology and Technology | (3-0)3 ECTS 8 |
| Contents include formal lectures covering basic concepts in development and homeostasis; ethical considerations in stem cell research and technology; embryonic stem cells; mesenchymal stem cells; neural stem cells and induced pluripotency. This course also demands students to understand and formally present recent articles in the field of stem cells. | ||
| BE 547 | Tissue Engineering and Regenerative Medicine | (3-0)3 ECTS 8 |
| Following topics will be covered in this course; cells and tissues, extracellular matrix, cell culture, biomaterials for tissue engineering, cell-biomaterial interaction, tissue modeling, tissue development, tissue and organ regeneration, stem-cell differentiation for regenerative medicine applications, tissue engineering methods, artificial tissue and organs. | ||
| BE 548 | 3D Cell Culture | (3-0)3 ECTS 8 |
| Biology of cells, cellular interactions, cell function, cell surface molecules, cell response, cell adhesion, cell motility, cytoskeleton, cell differentiation, materials for 3D cell culture, cell- material interaction and techniques in 3D cell culture will be covered during the course. | ||
| BE 549 | Nanomedicine | (3-0)3 ECTS 8 |
| This course has been designed to introduce nanomedicine field to students. The course covers the following topics: properties of biomaterials on the nanoscale, synthesis and processing of biomaterials at nanoscale, biofunctionalization of nanomaterials, smart nanomaterials for drug delivery and imaging applications, micro/nanofluidics for diagnosis and detection, new generation of imaging technologies, nanobiosensors (e.g. lab-on-a-chip), cellular nanomachines, regenerative medicine, including tissue engineering cell and gene therapy. | ||
| BE 591 | Special Topics in Bioengineering | (3-0)3 ECTS 8 |
| This course aims to evaluate and discuss a selected topic in the field of Bioengineering depending on the instructor’s expertise. | ||