In the Peptide and Protein Engineering Laboratory, we conduct research on the design and characterization of proteins. We perform computational and experimental characterization of protein interactions with themselves, other proteins, and small molecules. Analyzing these molecular interactions is crucial for developing diagnostic and therapeutic solutions in medicine, as it guides our research significantly. Additionally, optimizing these interactions through molecular design ensures the efficient functioning of the designed systems.

Ongoing Projects in Our Laboratory:

– Nanobody and Antigen Interaction: We experimentally and computationally study the interaction between a nanobody protein isolated from legumes and its antigen. This project is supported by TÜSEB (Group A) and is a collaborative effort with Uyar Laboratory.

– Diagnostic Platform Development: Our diagnostic platform project, which leverages nanobody-antigen interactions, is supported by YÖK (AU-DP) and involves collaboration with Bulmuş Laboratory.

– HIV-1 Capsid Protein Inhibitor Discovery: Supported by TÜSEB (Group A) and TÜBİTAK (1001), this project involves experimental and computational studies for discovering inhibitors of the HIV-1 capsid protein from pure natural products and microorganism extracts. This research is conducted in collaboration with Bedir and Uyar Laboratories.

– Biosimilar Drug Production and Characterization: We are also working on innovative methods for producing and analytically characterizing biosimilar drugs made from proteins and peptides.